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Хотя сегодня этот взгляд ставится под сомнение, см.: Joran Martijn, Julian Vosseberg, Lionel Guy, Pierre Offre, T. J. G. Ettema. Deep Mitochondrial Origin Outside the Sampled Alphaproteobacterial. Nature 557 (2018): 101-105. Doi: 10.1038/s41586-018-0059-5.
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[16] Piotrowska-Nitsche et al. Four-cell Stage Mouse Blastomeres, 479— 490; Morris et al. Developmental Plasticity Is Bound by Pluripotency, 756-765.
[17] Piotrowska-Nitsche, Zernicka-Goetz. Spatial Arrangement of Individual 4-Cell Stage Blastomeres, 487—500.
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[22] Ibid.
[23] Fernando H. Biase, Xiaoyi Cao, Sheng Zhong. Cell Fate Inclination Within 2-Cell and 4-Cell Mouse Embryos Revealed by Single-Cell RNA Sequencing. Genome Research 24. No. 11 (2014): 1787—1796. Doi: 10.1101/gr. 177725.114; Junchao Shi, Qi Chen, Xin Li, Xiu-deng Zheng, Ying Zhang, Jie Qiao, Fuchou Tang, Yi Tao, Qi Zhou, Enkui Duan. Dynamic Transcriptional Symmetry-Breaking in Pre-implantation Mammalian Embryo Development Revealed by Single-Cell RNA-Seq. Development 142 (2015): 3468—3477. Doi:10.1242/ dev. 123950.
[24] Мубин Гулам, электронное письмо Роджеру Хайфилду, 17 сентября 2018 года; Мубин Гулам, интервью с Роджером Хайфилдом, 23 августа 2018 года.
[25] М. Goolam, A. Scialdone, S. J. L. Graham, I. С. Macaulay, A. Jedrusik, A. Hupalowska, Т. Voet, J. C. Marioni, M. Zernicka-Goetz. Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos. Cell 165 (2016): 61-74. Dor 10 1016/i cell.2016.01.047.
[26] A. Jedrusik, D.-E. Parfitt, G. Guo, M. Skamagki, J. B. Grabarek, M. H. Johnson, P. Robson, M. Zernicka-Goetz. Role ofCdx2and Cell Polarity in Cell Allocation and Specification of Trophectoderm and I
[27] Goolam et al. Heterogeneity in Oct4andSox2 Targets, 61-74.
[28] M D. White, J. F. Angiolini, Y. D. Alvarez, G. Kaur, Z. W. Zhao, E. Mocskos, L. Bruno, S. Bissiere, V. Levi, N. Plachta. Long-Lived Binding of Sox2 to DNA Predicts Cell Fate in the Four-Cell Mouse Embryo. Cell 165 (2016): 75-87. Doi: 10.1016/j.cell.2016.02.032.
[29] Ibid.
[30] S. A. Morris, Y. Guo, M. Zernicka-Goetz. Developmental Plasticity Is Bound by Pluripotency and the Fgfand Wnt Signaling Pathways. Cell Reports 2. No. 4 (2012): 756-765.
[31] N. Plachta, T. Bollenbach, S. Pease, S. E. Fraser, P. Pantazis. Oct4 Kinetics Predict Cell Lineage Patterning in the Early Mammalian Embryo. Nature Cell Biology 13 (2011): 117-123. Doi: 10.1038/ncb2154.
[32] White et al. Long-Lived Binding of Sox2 to DNA, 75-87.
[33] 1. Tabansky, A. Lenarcic, R. W. Draft, K. Loulier, D. B. Keskin, J. Rosains, J. Rivera-Feliciano, J. W. Lichtman, J. Livet, J. N. Stern, J. R. Sanes, K. Eggan. Developmental Bias in Cleavage-Stage Mouse Blastomeres. Current Biology 23 (2013): 21-31. Doi: 10.1016/j cub.2012.10.054.
[34] Ibid.
Глава 6. Вскрытие черного ящика
[1] J. W. Lichtman, S. E. Fraser. The Neuronal Naturalist: Watching Neurons in Their Native Habitat. Nature Neuroscience 4 (2001): 1215-1220. Doi:10.1038/
[2] Insoo Hyun, Amy Wilkerson, Josephine Johnston. Embryology Policy: Revisit the 14-Day Rule. Nature 533 (2016): 169-171. URL: www. nature.com/news/embryology-policy-revisitthe- 14-day-rule-1.19838.